He is the head of the Laboratory of Selective Oxidation Catalysis at N. D. Zelinsky Institute of Organic Chemistry of the Russian Academy of Sciences.
In 2016, Konstantin Bryliakov was elected professor of the Russian Academy of Sciences.
Konstantin Bryliakov pioneered the use of homochiral metal-organic frameworks as chiral stationary phases for chromatographic separation of enantiomers.
[13] Konstantin Bryliakov developed a variety of biomimetic approaches to molecular editing of complex organic molecules via direct selective activation and heterofunctionalization of aliphatic C-H groups.
Winner of the President of Chinese Academy of Sciences International Fellowship Award for 2020.