[5] Radhe Lal Shukla lives in Kanpur, Uttar Pradesh and belongs to a rich yet illiterate family.

Humiliated for his illiteracy, his dominating and arrogant non-biological father Gajodhar chooses district-topper Krishna Dubey as his bride from the neighboring town of Malihabad.

Krishna dreams of studying medicine in London and becoming a doctor, but still marries Radhe for her father's reputation.

She is humiliated by the Shukla family members who resent her for independent thoughts and modern views.

In medical school, Krishna is punished by stern and arrogant NRI professor Dr.

Heartbroken, Krishna returns the hospital to Gajodhar and leaves for London to complete medical school.

Krishna is now an honest and sincere professional doctor working at the Life Care Hospital.

Veer and Krishna reject an appointment letter from the London Royal Hospital to stay back in Kanpur with the Shukla family who give them their blessings.

Both the leads not hailing from backdrop of the series Kanpur, went on training to learn the accent and slang used there.

I read a lot of books and watched movies in the languages spoken in and around eastern Uttar Pradesh.

When I was approached for the show, my character required me to learn a local dialect of Uttar Pradesh, which is very close to the Hindi language.

[11] In early January 2019, to increase the ratings, Sareen was made to quit the series when his character was killed in a car accident in London which he was informed the day before shooting the sequence.

[10][13] It was remade in Kannada as Nan Hendthi MBBS, which premiered on Star Suvarna on 11 February 2019 and ended on 18 May 2019 with 82 episodes due to low viewership.

[21][22] With its decent average ratings, it maintained its position in weekly top twenty Hindi GEC in urban since its premiere until December 2018.