Directed by Erick C. Salud, Trina N. Dayrit and Dondon S. Santos,[1][2] The series features an ensemble cast consisting of Kris Aquino, Gabby Concepcion, Albert Martinez, Gina Pareño, Jaclyn Jose, Maricar Reyes, Gerald Anderson, Coco Martin, Max Eigenmann, Jessy Mendiola and Kim Chiu.

While grieving the loss of her husband, she also discovered that Frank had an affair with Astrud and they had a love child named Ringo.

To make things more complicated, Gwen, who has grown into a pretty young lady, meets Robbie, the younger brother of Selina.

[1] On November 25, 2009, ABS-CBN released a teaser via their official YouTube account identifying the cast and characters.

[6] For the third time, Gary Valenciano sang the theme song for a series which stars Kim Chiu and Gerald Anderson.

The title of the series was derived from the song, "Kung Tayo'y Magkakalayo", which was originally sung by Rey Valera and covered by Gary Valenciano for the show.

The show premiered with a 34.4% household rating in the GMA Network-dominated Mega Manila Area.

ABS-CBN's Agua Bendita tied with GMA's Endless Love with 14.4 people rating each.