The Kuno clan (Japanese: 久野氏, Hepburn: Kuno-shi) was a Japanese samurai clan who were a prominent Jizamurai (国人 kokujin) family of Tōtōmi Province during the Muromachi period and Sengoku period.

They first served the Imagawa clan (今川氏) for generations but later became retainers of Tokugawa Ieyasu.

The surname is sometimes written as "久努", "久奴" or "久能".

His fifth generation great-grandson, Fujiwara no Tamenori (藤原為憲), founded the Kudō clan.

Another theory is that the Kuno are descendants of the Hata clan (秦氏), an immigrant family who claimed descent from the first Emperor of China, Qin Shi Huang.