Kupinovo (Serbian Cyrillic: Купиново, Glagolitic script: Ⰽⱆⱂⰻⱀⱁⰲⱁ) is a village located in the municipality of Pećinci, Serbia.

In the Middle Ages, Kupinik was a notable city and was a residence of Serbian Despots in Syrmia in the 15th and 16th century.

It was built as a military-border fortification on the border between Kingdom of Hungary and the Principality of Moravian Serbia.

In the early 15th century Stefan Lazarevic, Prince of Serbia, member of the ruling Lazarević dynasty received Kupinik from the King Sigismund of Hungary.

After the death of Đurađ Branković, Kupinik was once again taken over by the Hungarian King who gave it to the Berislavić family, whose members held the titular title of Despot of Serbia.