[1] Kuwana-juku was located in the castle town of Kuwana Domain, which was a major security barrier on the Tōkaidō for the Tokugawa shogunate.

The preferred connection for many travelers between Kuwana-juku and Miya-juku was by the Shichiri no watashi (七里の渡し), a roughly 28-kilometer boat ride across Ise Bay.

A large torii gate on the Kuwana side of the crossing indicated that this was also on the route for pilgrims to the Ise Grand Shrine.

For those leery of travel on the ocean, the alternative was the Saya Kaidō (佐屋街道), which consisted of a shorter riverboat ride, the Sanri no watashi (三里の渡し) which connected Kuwana-juku with Saya-juku (佐屋宿), a post station in Owari Province, and thence overland via the Saya Kaidō highway to Miya-juku, with three intermediate post stations en route.

The popular local specialities of Kuwana-juku was grilled hamaguri clams, whitebait and banko ware pottery.