[4] After his studies at the training college, Karikari began teaching at the Wenchi Experimental Primary School, Ashanti-Akim.
[5] In 1971, Karikari left for the United States to study at the City College of New York.
[1][5] He graduated from City College in 1975 with a bachelor of arts degree in philosophy and political science.
[2][9][10] Kwame Karikari later joined the Wisconsin University in Ghana as Dean of Communications Studies.
[2] As an activist of freedom of expression, social justice and democracy in Africa, Karikari served as the Executive Director of the Media Foundation West Africa (MFWA),[2][11][12] he has also served various boards and international organisations that champion human rights.