2OTP11027n/aENSG00000239998ENSG00000274000ENSG00000275290ENSG00000278634n/aQ8N149n/aNM_001130917NM_001290270NM_001290271NM_006866n/aNP_001124389NP_001277199NP_001277200NP_006857n/aLeukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2, CD85H, ILT1) is a protein that in humans is encoded by the LILRA2 gene.

LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades.

One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.

[supplied by OMIM][5] LILRA2 senses microbially cleaved immunoglobulin to activate human myeloid cells.

[6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.