1G0X, 1P7Q, 1UFU, 1UGN, 1VDG, 3D2U, 4LL9, 4NO010859n/an/an/aQ8NHL6n/aNM_006669NM_001388355NM_001388356NM_001388357NM_001388358n/aNP_006660n/aLeukocyte immunoglobulin-like receptor subfamily B member 1 is a protein that in humans is encoded by the LILRB1 gene.

The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).

The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response.

Multiple transcript variants encoding different isoforms have been found for this gene.

You can help Wikipedia by expanding it.This article incorporates text from the United States National Library of Medicine, which is in the public domain.