1102518729ENSG00000275019ENSG00000274587ENSG00000277816ENSG00000204577n/aQ6PI73O75022n/aNM_001081450NM_006864NM_001320960NM_001289428NM_008848NM_011093XP_006726238.1XP_006726376XP_006726377XP_011546876XP_011546877n/aLeukocyte immunoglobulin-like receptor subfamily B member 3 is a protein that in humans is encoded by the LILRB3 gene.
The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs).
The receptor is expressed on immune cells and is believed to be a myeloid checkpoint.
Multiple transcript variants encoding different isoforms have been found for this gene.
[6] This article incorporates text from the United States National Library of Medicine, which is in the public domain.