[1] It is generally considered a non-selective research tool, and should not be used for experiments aiming to target PI3K uniquely.
[2] Two of these are the proto-oncogene serine/threonine-protein kinase (PIM1) and the phosphatidylinositol-4,5-bisphosphate 3-kinase P110 gamma|catalytic subunit gamma isoform.
[3] With an IC50 of 1.4 μM it is somewhat less potent than wortmannin, another well-known PI3 kinase inhibitor.
[4] Application of LY294002 causes a substantial acceleration of MEPP frequency (150 μM) at the frog neuromuscular junction through a mechanism that is independent of intraterminal calcium.
[6] It has been shown that LY294002 administration has an additive effect on quercetin antiviral activity against hepatitis C virus.