"La Despedida" (English: "The Farewell") is a single by Puerto Rican reggaeton singer Daddy Yankee.

It is the third official single released on August 4, 2010 from his album Mundial.

[1] The official remix of the song features American singer Tony Dize.

Matthew Wilkening from AOL Radio Blog said that the song "combines an infectious mid-tempo dance beat with Latin horns and percussion, as Daddy Yankee bids farewell — but seemingly refuses to give up a lover who is moving away from him, despite his friends' best advice".

It was directed by George Rivera and Juan Esteban Suárez.