La Salle University Ozamiz, Inc. is a private Catholic Lasallian coeducational basic and higher education institution run by the Philippine District of the Christian Brothers in Ozamiz City, Misamis Occidental Philippines.

The history of La Salle Ozamiz dates back to the establishment of a parochial school in 1789 within the Parish of the Immaculate Conception.

Peter Fallon, SSC became the first Director of the Immaculate Conception School and that year witnessed the first graduation.

However, World War II broke out and classes had to be discontinued and the old convent, which was used as a school building was converted into a Japanese headquarters.

In 1990, the De La Salle Brothers agreed to assist in the academic supervision of the school with Br.

[2] On September 14, 2006, upon the establishment of De La Salle Philippines, the College officially became a District school.

Rey Erezare Mejias FSC is La Salle University's current President.