Except for the small patch of the Danube's right bank which is in Central Serbia, all of the reserve is located in the province of Vojvodina, in the municipalities of Kovin and Bela Crkva.

Labudovo okno is situated in the southern rim of the Pannonian Plain, between the Deliblatska peščara on the north and the Danube's section of Ram Lake in the south.

It developed when hydroelectrical plant Đerdap I began to fill its reservoir in the late 1960s, due to the backwater of the Danube so the water flooded surrounding plains.

[3] The area of the Deliblatska peščara, which is the major sandplain, is arid and has no springs or creeks but in the alluvial plains of the Danube underground water forms permanent ponds in the hollows made by the wind in the sand.

Examples of the plants inhabiting the wet plains include pheasant's eye, glandular globe-thistle, Small yellow onion and mushrooms.

Hygrophilous forest are populated with the willow, poplar, pedunculate oak and the endangered Hungarian thorn, old man's beard shrubs and fungi.

It is locally called mazer, can live up to 300 years and is highly valued as a furniture material as its natural knots appear as dark roses on the white wood.

[2] Given the size of the population of the Ponto-Caspian and Eastern Mediterranean elements, Labudovo okno is the most important center of the diversity of this type of fauna in Europe.

Marshes and shallows are an ideal natural spawning location for some 50 species of fish,[2] which include common carp, northern pike, wels catfish, and sterlet.

Later stories involve the mythical wooden temple on the Dubovac Island, built by the ancient Slavs and dedicated to the gods Perun, Veles, and Wodan.

During the Informbiro period in Yugoslav-Soviet relations after 1948, expecting the possible invasion from the Soviet block, the area was adapted into the Belgrade's first line of defense against the potential attack.

St. George Shoots the Dragon, a movie directed by Srđan Dragojević and based on the drama of the same name by Dušan Kovačević, was filmed in the area in 2008.

Environmental agencies from both provincial and state level organized to make a plan to tighten the protection and possibly turn Labudovo okno into the ecotourism destination.