It was established as Lahore Medical School during the British Raj in 1860 and is named after King Edward VII.

Pakistan's first Spinal Cord Stimulation surgery was done by Neurosurgery Department of King Edward Medical University / Mayo Hospital Lahore in August 2018.

[8] The team included Professor Shahzad Shams (Chairman[9][10] Neurosurgery King Edward Medical University / Mayo Hospital Lahore), Dr Muhammad Tariq [11](Asst Prof Neurosurgery King Edward Medical University, Lahore), Dr Ammar Anwer[12] (Research Fellow ANFN-DBS Pakistan) and Dr Rupesh Jung Raut[13] (R 3, Neurosurgery Department King Edward Medical University / Mayo Hospital Lahore).

The patient was suffering from phantom limb syndrome and Medtronic Prime Advance™ SCS[14] system was implanted bilaterally in cervical spine.

Another building was constructed with the help of Maqbool Ahmad, M.D., a notable Kemcolian, who donated 9 million dollars for the new structure.

This block also features the Asad Aslam Auditorium and the Samina Hall, the focal venues of most university events.

[citation needed] King Edward Medical University is headed by the Vice Chancellor; this title is currently being served by Prof. Dr. Mahmood Ayaz.

[18] After completion of the internship the full registration status to a Doctor is awarded by Pakistan Medical and Dental Council (PMDC).

[citation needed] King Edward Medical University Magazine, KEMCOL, is maintained by the students.

[19] David Waters Sutherland CIE FRSE (18 December 1872–19 April 1939) was an Australian physician who ran the King Edward Medical College in Lahore and married Princess Bamba Singh.