[4] Lake Manchar collects water from numerous small streams in the Kirthar Mountains, and then empties into the Indus River.

[6][7] The lake's banks and vicinity are home to ancient archaeological sites Ghazi Shah, Wahi Pandhi and Ali Murad Mound.

[16] Engineers made a breach in the lake to assist its drainage to protect the city of Sehwan and the town of Bhan Syedabad, at the cost of flooding many villages that are home to 150,000 people.

[13] The southern end of the lake is at the base of the Laki Hills, a branch of the Kirthar Mountains, and water flows to the Indus via the Aral channel,[18] and Danister Canal.

[20] The lake since construction of the Main Nara Valley Drain in 1921 has undergone environmental degradation with inflow of sewage.

At the same time, saline drainage water from agricultural fields of Balochistan and surrounding areas flows into Lake Manchar.