It is formed in northern Morgan County, about 4 miles (6 km) southeast of Otterville by the confluence of Flat and Richland creeks, and flows generally northwardly through Cooper and Pettis counties.
In northwestern Cooper County the Lamine collects the Blackwater River and flows into the Missouri River northeast of Lamine and 6 miles (10 km) west of Boonville.
[2] At Clifton City, the river has a mean annual discharge of 455 cubic feet per second.
)The river was named by French explorers for mining operations in the area.
This article related to a river in Missouri is a stub.