[2] Mackenzie studied printmaking at both NSCAD and Concordia, it was not until after completing art school that she began to fully pursue a career in painting.
[2] Aware of the limits placed on many female artists, Mackenzie used her name "Landon", which is commonly used as boys name, to her advantage in the early years of her career, as she has said "people thought I was a guy".
Her paintings have also been exhibited at the Museum of Contemporary Canadian Art and in many solo and group shows in Canada and internationally, over the past thirty years.
In her graduate school period in Montreal at Concordia University, from 1976–1979, Mackenzie developed her own voice as a more mature artist at a time of heightened contest between the acclaimed painters and sculptors involved in the last throes of high Modernism and the beginnings of a Post-Modern consciousness in art practice.
[3] In several of her large-scale paintings from the early 1990s to 2009, Mackenzie layered research notes, annotated maps, archival texts and documentation of her investigations and explorations of geographic regions.