From 1389 to 1396, Sir Alexander Cockburn of Langton was the Keeper of the Great Seal of Scotland.
In a dispute over succession to the estate, the castle was besieged by William Cockburn and his brother in law, David Home of Wedderburn in 1517.
Antoine d'Arces, Sieur de la Bastie, the French deputy for Regent Albany, summoned Cockburn and Home to resolve the dispute.
They in turn broke off the siege and ambushed Bastie near Preston, there they slew him and displayed his head at the Mercat cross of Duns.
Gavin married Lady Elizabeth Maitland, daughter of James Maitland, 7th Earl of Lauderdale, their daughter Mary married John Campbell, 1st Marquess of Breadalbane whose descendant demolished the house and built a final Langton House in 1886 designed by David Bryce.