The school paused operations in 1821 due to the Greek War of Independence, resuming in 1834 as a three-year institution.

From 1870 to 1913, Andreas Themistokleous (Greek: Ανδρέας Θεμιστοκλέους), son of Demetrios, served as principal, pioneering physical education in Limassol's schools.

In 1945, Nicolas P. Lanitis (Greek: Νικόλαος Π. Λανίτης) significantly contributed to constructing a new school building, now housing the Laniteio Lyceum.

Following the events of 1974, and the sudden influx of refugee students, the 8th Gymnasium of Limassol[d] started operating in the Laniteio school area.

Laniteio, along with the 5th Gymnasium, managed morning and evening schedules to accommodate the large number of students.