[1] LIMR focuses on studies of cancer, cardiovascular, autoimmune, gastrointestinal and other diseases.

[3][4] LHRI researcher David Hungerford is credited with the discovery of the first genetic abnormality in cancer, called the Philadelphia chromosome.

The first molecule-targeted drug to be created for cancer therapy, Gleevec (imatinib), acts by blocking this genetic abnormality.

[citation needed] LHRI researcher Baruch Blumberg is credited with the discovery of the hepatitis B virus and a blood test to detect it, as recognized by the 1976 Nobel Prize for Physiology or Medicine.

[6] LIMR carried out research into the role of IDO (indoleamine 2,3-dioxygenase) in cancer, including the first experimental therapeutics to directly inhibit this enzyme, which modifies inflammatory processes in cancer, autoimmune disease, retinopathy, cardiovascular disease, and other disorders.