Berenice or Laodice of Cappadocia, also known as Laodice (Ancient Greek: Λαοδίκη Laodíkē; flourished from the mid-120s BC to the 90s BC) was a princess from the Kingdom of Pontus and a queen of the Kingdom of Cappadocia by marriage to Ariarathes VI, and queen of Bithynia by marriage to Nicomedes III.

She had been the wife and later the widow of the previous Cappadocian King Ariarathes V.[2] Mithridates V was aware of the turbulent political situation in Cappadocia, which ended in the death of his sister, Nysa.

[3] In the mid 120s BC, he became interested in Cappadocia and wanted to expand Pontian foreign policy in that country.

[5] To fend off any Pontian invasion, Ariarathes VI arranged with Mithridates V to marry Laodice, his paternal cousin.

[5] There is a possibility that the invasion of Mithridates V was in fact friendly on behalf of Ariarathes VI to settle internal Cappadocian strife and help him to establish himself as a ruler.

There could be a possibility that Pontian political influence in Cappadocian affairs may have declined as Ariarathes VI became independent minded and began to assert himself.

[7] Laodice’s former son-in-law and a widower, King Nicomedes III Euergetes, wanted to take advantage of the political situation in Cappadocia.

He then pretended that he wanted to recall Gordius from exile hoping that Ariarathes VII would oppose this, thus giving him a pretext for war.

Nicomedes pretended that Laodice had a third son from him and sent a young man to Rome to apply for the throne of Bithynia from the Roman Senate.

It provided for the erection of a statue of the king and one of queen in the most prominent place in the temple of Pythian Apollo and for the grant to the two monarchs and their descendants of proxeny, priority of access to the oracle of Delphi and in receiving justice, tax exemption, privileged seating at the city’s games and other privileges that were given to other proxenoi[12] and other benefactors of the city.

[14] She is remembered in De Mulieribus Claris, a collection of biographies of historical and mythological women by the Florentine author Giovanni Boccaccio, composed in 1361–62.