[2][3] It is used widely in medicine, some representative research work about it are these: [4][5][6] The eye offers a unique opportunity for the non-invasive exploration of cardiovascular diseases.

LDI provides high-contrast visualization of local blood flow in choroidal vessels in humans, with a spatial resolution comparable to state-of-the-art indocyanine green angiography.

[9] The local velocity of blood flow measured by laser Doppler holography in the digit (photoplethysmogram) and the eye fundus has a pulse-shaped profile with time.

LDI provides a direct measure of female sexual response that does not require genital contact; signals are gathered at a depth of two to three millimetres below the skin's surface.

[11][12] Waxman and Pukall[11] showed that LDI has discriminant validity; that is, it can differentiate sexual response from neutral, positive, and negative mood induced states.