[5] She was a debutante, making her formal debut in a Dior haute couture gown at le Bal des débutantes in Paris in 2000.

She has been featured on the covers of Vogue and Vanity Fair and has frequently modelled for Tommy Hilfiger, as well as for Abercrombie & Fitch and designers Gai Mattiolo and Isaac Mizrahi.

[8] In 2005, Bush traveled to Chad as a Student Ambassador for the World Food Program.

[11] Bush relaunched her fashion label on September 11, 2008, under the name "Lauren Pierce".

[13] FEED Projects has donated over 100 million meals as of October 2017[14] through the sale of products and fundraising activations.

In 2015, she signed an open letter for which the ONE Campaign had been collecting signatures; the letter was addressed to Angela Merkel and Nkosazana Dlamini-Zuma, urging them to focus on women as they serve as the heads of the G7 in Germany and the AU in South Africa, respectively, which would start to set the priorities in development funding before a main UN summit in September 2015 to establish new development goals for the generation.

[24] Their second son, Max Walker Lauren, was born on April 19, 2018, two days after Barbara Bush died.