Her other notable TV roles include Bela Talbot in the dark fantasy drama Supernatural (2007–2008), Rose in the supernatural teen drama The Vampire Diaries (2010–2012), Vivian McArthur Volkoff in the action comedy Chuck (2011), Francesca "Frankie" Trowbridge in the action comedy-drama Whiskey Cavalier (2019), and War Woman in the adult animated superhero show Invincible (2021-present).

Cohan was born Lauren Storholm in Cherry Hill, New Jersey, to an American father and a British immigrant mother from Scotland.

She also guest starred on shows such as Archer, Cold Case, CSI: NY, Life, and Modern Family.

Cohan starred in a pilot for The CW called Heavenly (2011) in which she played the lead character, Lily, an attorney who teams up with an angel; however, it was not picked up as a series.

[20] At the conclusion of the eighth season of The Walking Dead, Cohan completed her contract obligations as a series regular.

[21] Cohan eventually reached an agreement to appear in five episodes in the first half of season nine of The Walking Dead[22] and departed the series in 2018.

[23] In early 2018, in the midst of her contract negotiations with AMC regarding The Walking Dead, Cohan was cast as CIA operative Francesca "Frankie" Trowbridge in the ABC action comedy-drama Whiskey Cavalier.