She also received another Emmy nomination for Outstanding Actress in a Short Form Comedy or Drama Series for her performance in Cooper's Bar.

[2] She soon started getting parts in more television productions, often playing roles that she considered as "very wry, sarcastic, knowing women," similar to her idol Bea Arthur.

[2] Among her early roles was the lead in a pilot for an American version of the Argentine telenovela Lalola, about a womanizing executive who gets turned female through witchcraft as revenge for his treatment of women, entitled Eva Adams, and was filmed for the Fox network co-starring James Van Der Beek in 2009.

In May 2014, Seehorn was cast in the Breaking Bad spin-off prequel series Better Call Saul (2015–2022), created by Vince Gilligan and Peter Gould.

[8][9] Seehorn portrays Kim Wexler, a lawyer and the love interest of the titular Jimmy McGill / Saul Goodman (Bob Odenkirk).

[12] In 2022, Seehorn made her television directorial debut with the fourth episode of Better Call Saul's final season ("Hit and Run").