Leading Creek is a tributary of the Little Kanawha River, 28.6 miles (46.0 km) long,[3] in central West Virginia in the United States.

Via the Little Kanawha and Ohio rivers, it is part of the watershed of the Mississippi River, draining an area of 147 square miles (380 km2)[4] in a rural region on the unglaciated portion of the Allegheny Plateau.

It flows into the Little Kanawha River approximately 2.4 miles (3.9 km) west-northwest of Glenville.

[5] Between Camden and Troy, the creek's course is paralleled by the Staunton and Parkersburg Turnpike, along present-day U.S. routes 33 and 119 between Camden and Linn; and West Virginia Route 47 between Linn and Troy.

[5][6] According to the West Virginia Department of Environmental Protection, approximately 84% of the Leading Creek watershed is forested, mostly deciduous.