The railway infrastructure is managed by the Rete Ferroviaria Italiana, which classifies it as one of its complementary lines.

The railway from Lecco to Bergamo was built by the Società delle Strade Ferrate della Lombardia e dell'Italia Centrale (Lombardy and Central Italy Railway Company) and opened on 4 November 1863.

In 2015, the Province of Bergamo, the region of Lombardy and some local parliamentarians requested and obtained government funding for the doubling of the section between Ponte San Pietro and Montello, the building of the new Bergamo Ospedale station at the Papa Giovanni XXIII hospital and a suburban service between the two Bergamo stations.

The service includes a train every hour throughout the day, present both on weekdays and on holidays.

In addition to the trains departing from Lecco at 6.30 and 7.02 and from Bergamo at 6.08 and 7.00, the timetable includes departure at 12 minutes past the hour from Lecco between 8 a.m. to 9 p.m. and at 8 minutes past the hour from Bergamo from 8 a.m. to 9 p.m.