Newton was a founding member of the production company and web-series known as The Valleyfolk, in which she was a co-host alongside fellow former SourceFed hosts Joe Bereta, Elliott Morgan, and Steve Zaragoza.

[7] On March 2, 2012, a video was posted to her brother Jake Newton's YouTube channel of the two singing a song cover of Whitney Houston's "I Wanna Dance With Somebody".

[15][16] Newton first rose to prominence online as the co-host of SourceFed, a YouTube pop culture & news channel.

[21][22] On 3 April 2012, Maxim posted a list of the most popular 'write-in' candidates, and included Lee Newton, writing that she had 'list potential'.

In March 2013, Newton appeared alongside SourceFed co-host Steve Zaragoza and creator Philip DeFranco in a Taco Bell advertisement.

[29] Also in May 2013, Newton appeared in an episode of the Fine Brothers's YouTubers React, alongside SourceFed co-host, Steve Zaragoza.

[34] Newton also voice acted as Tanya Burkowitz and Katelynn Zales in the stop-motion animated web series The Most Popular Girls in School, in 2013.

[36] In 2018, Newton along with founding SourceFed hosts Joe Bereta, Elliott Morgan, and Steve Zaragoza, launched a production company and YouTube channel entitled The Valleyfolk.

[41] That July, Newton was announced to be included in the cast of Comedy Central's series, CC: Social Scene.