Orazio later commissioned Borromini to renovate the church of San Giovanni dei Fiorentini to build a Falconieri family chapel for the burial of the two brothers.
[3] At a young age he went to Rome and became an advocate at the Roman Curia and papal prelate during the pontificate of Pope Paul V. In 1619 he became Governor of San Severino and a referendary of the Tribunals of the Apostolic Signatura of Justice and of Grace.
Maffeo Barberini was elected Pope Urban VIII at the Papal conclave of 1623 and during his pontificate, Falconieri became the relator of the Sacred Consulta and commissary general of Umbria and Romagna.
[5] Between 1635 and 1637 he was named papal nuncio to Flanders, but after being informed in Liège that the government of Philip IV of Spain opposed his appointment he returned to Rome on grounds of ill health.
Pope Urban elevated Falconieri to cardinal in the consistory of 1643 and he was named Cardinal-Priest of Santa Maria del Popolo later that year.