The Lenne Mountains lie in the Sauerland within the districts of Märkischer Kreis, Olpe and Hochsauerlandkreis.

The uplands are crossed from southwest to northeast by a section of the B 229 federal road and the B 236 passes along its southwestern perimeter in a northwest–southeast direction.

Other hills are the Schomberg (648 m), Waldeshöhe (625.8 m), Baukloh (616.0 m), Reinscheid (573.0 m), Denstenberg (560.0 m), Kohlberg (513.7 m), Hommert (504.8 m) and Kleiner Hemberg (497.2 m).

The largest river in the region is the Lenne itself, whose middle course grazes the hills to the south and southwest.

The Sorpesee is a lake in the northern part of the range, in the south is the Glingebach Dam and in the east the Esmecke Reservoir.