He continued a path in medicine initiated by his older brother, Hyman I. Goldstein.
He was chief of gynecology and obstetrics at Einstein Medical Center, Associate Professor at Thomas Jefferson University Medical Center, and an associate of the Gynecology Department of the University of Pennsylvania, all of Philadelphia, PA. During the late 1920s, Goldstein undertook postgraduate studies in Vienna, Austria, and the Rotunda Hospital in Dublin.
He co-authored, "Clinical Endocrinology of the Female" with Charles Mazer, published in Philadelphia and London by W.B.
He also was the author of over forty articles in his specialty published in respective medical journals during his career, and was a proponent of the use of the colposcopy in physical examinations of female patients.
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