Lewisburg High School is a suburban public high school located in Lewisburg, Mississippi, United States (with an Olive Branch postal address).

Its mascot is the Patriot, and its school colors are red and navy.

It is operated by the DeSoto County School District.

[2] In 2006, Lewisburg High School opened under the direction of Principal James Brady.

The school opened with few extra-curricular activities to offer.