Some authors split the process of liberation into three steps: disintegration, disaggregation and dissolution.
The characteristics of a medication's excipient play a fundamental role in creating a suitable environment for the correct absorption of a drug.
The rate of dissolution is a key element in controlling the duration of a drug's effect.
In addition, a slow release system will maintain drug concentrations within a therapeutically acceptable range for longer than quicker releasing delivery systems as these result in more pronounced peaks in plasma concentration.
Cell membranes present a greater barrier to the movement of ionized molecules than non-ionized liposoluble substances.