Lionello Levi Sandri (5 October 1910 in Milan – 14 April 1991 in Rome) was an Italian politician and European Commissioner.

Upon completing his education in 1932, Levi Sandri entered a career as a civil servant in the Italian employment administration and was promoted to high-ranking posts at a young age.

Following the armistice on 8 September 1943 and the related events, however, he chose to join the resistance movement against Benito Mussolini, where he came to lead the partisan formation "Fiamme Verdi" (Green Flames) in the Brescia region.

After the war, Levi Sandri became involved in the Italian Socialist Party (PSI).

[1] He was appointed to the first European Commission in December 1960 (or February 1961) as the successor to Giuseppe Petrilli in the Hallstein Commission and was responsible for the Social Affairs portfolio, in addition to overseas states and territories.