[3] People with lipodermatosclerosis have tapering of their legs above the ankles, forming a constricting band resembling an inverted champagne bottle.

[3] The origin of lipodermatosclerosis is probably multifactorial, involving tissue hypoxia, leakage of proteins into the interstitium, and leukocyte activation.

Capillaries are virtually absent in areas of fibrotic scars, leading to a condition known as atrophie blanche or livedoid vasculopathy.

[9] The management of lipodermatosclerosis may include treating venous insufficiency with leg elevation and elastic compression stockings.

Note: This article contains material adapted from the public domain source "Lipodermatosclerosis: Questions and Answers", by the U.S federal government's Genetic and Rare Diseases Information Center