Lippia substrigosa is a plant from the family Verbenaceae that is native to Central and South America.

It can grow as either a shrub or a tree up to 7 metres (23 ft) tall and can be burned to produce fuel.

Lippia substrigosa is native to southern Mexico, Guatemala, Honduras, El Salvador, and Nicaragua.

In Guatemala, L. substrigosa can be found in the departments of Alta Verapaz, Baja Verapaz, Chimaltenango, Chiquimula, Guatemala, Huehuetenango, Jalapa, Quetzaltenango, El Quiche, Sacatepéquez, San Marcos, Santa Rosa, Sololá, and Zacapa.

It has been found at altitudes from 1,200 to 2,800 metres (3,900 to 9,200 ft) and can grow in oak-pine forests, open rocky slopes, and in wet or dry thickets.

At their tips, leaf blades are acute to acuminate (tapering to a sharp point), while at their base, they are either cordate to abruptly contracted and obtuse or long, slender and wedge shaped.

However, it may be burned for fuel and research is being conducted to determine the potential benefits of its essential oil.

L. substrigosa has a high concentration of various sesquiterpenes, some of which are found frequently in the oils of other Lippia species.

Therefore, although the essential oils of Lippia species vary from each other in concentration and composition of chemical compounds, L. substrigosa may produce an oil that has medicinal benefit or a cosmetic use due to genetic similarities among species in the genus Lippia.