Sesquiterpene

Sesquiterpenes are a class of terpenes that consist of three isoprene units and often have the molecular formula C15H24.

The FPP backbone can be rearranged in several different ways and further decorated with different functional groups, hence the large variety of sesquiterpenoids.

Geosmin, the volatile compound that gives an earthy taste and musty odor in drinking water and the characteristic odor on a rainy day, is a sesquiterpenoid, produced by bacteria, especially cyanobacteria, that are present in the soils and water supplies.

They are found in many plants and can cause allergic reactions and toxicity if consumed excessively, particularly in grazing livestock.

[9] The term merosesquiterpenoids was coined in 1968 to describe molecules of this class that have a mixed biosynthetic origin, meaning isoprenoid precursors like isopentenyl pyrophosphate are derived from both the mevalonate and non-mevalonate pathways.