[3] They have a record of 22 wins, 21 losses and 1 tie in Opening Day games at Wrigley Field.
Larry Corcoran, Clark Griffith, Grover Cleveland Alexander, Charlie Root and Rick Sutcliffe have each made five Opening Day starts for the Cubs.
Orval Overall, Lon Warneke, Bob Rush, Larry Jackson and Rick Reuschel each made four Opening Day starts for the Cubs, and Bill Hutchison, Jon Lieber, Ray Burris, Claude Passeau, Jack Taylor and Hippo Vaughn each made three such starts.
Five Cubs' Opening Day starting pitchers have been inducted into the Baseball Hall of Fame: Griffith, Alexander, Jenkins, Al Spalding and John Clarkson.
[4] In addition, 300–game winner Greg Maddux was the Cubs' Opening Day starting pitcher in 1992.