Most of the destruction blamed on him is actually caused by the extreme measures people take to capture or kill him for the reward; as a result, he has been nicknamed "The Humanoid Typhoon."
The anime was directed by Satoshi Nishimura at Madhouse, with Yōsuke Kuroda handling series composition, Takahiro Yoshimatsu providing character designs, and music composed by Tsuneo Imahori.
In the United Kingdom, the anime was released on DVD by MVM Films, starting in 2005 and projected to be finished by the end of 2006 (there were delays due to a fire at a disc duplication plant in August 2005)[citation needed].
He reflects on the past 130 years since Knives caused the crash of the Project SEEDS fleet and became determined to wipe out all humans on the planet.
Taken in by the residents of the Project SEEDS ship that had stayed aloft, Vash located a descendant of Rem in July and traveled there to meet him, only to find him dead at the hand of Knives.