List of Major League Baseball players from the Dominican Republic

This is an alphabetical list of notable baseball players from the Dominican Republic who have played in Major League Baseball since 1950.

Players in bold are still active in MLB, as of 2022.

Since 1956 a large number of baseball players of Dominican origin have played in Major League Baseball in the United States, with the Dominican Republic being the second country in the world after the United States with the most current baseball players in MLB.

^These three form the SSS islands that with the ABC islands comprise the Dutch Caribbean, of which *the BES islands are not direct Kingdom constituents but subsumed with the country of the Netherlands.

†Physiographically, these continental islands are not part of the volcanic Windward Islands arc, although sometimes grouped with them culturally and politically.