List of Major League Baseball players from the United States Virgin Islands

This is a chronological list of baseball players from the United States Virgin Islands who played in Major League Baseball between 1957 and 2017 ^These three form the SSS islands that with the ABC islands comprise the Dutch Caribbean, of which *the BES islands are not direct Kingdom constituents but subsumed with the country of the Netherlands.

†Physiographically, these continental islands are not part of the volcanic Windward Islands arc, although sometimes grouped with them culturally and politically.

ǂDisputed territories administered by Guyana.

~Disputed territories administered by Colombia.