Wine grapes were grown in Florida earlier than anywhere else in North America.

[6] The Florida Wine Grape Growers Association (FWGGA) was established in 1923.

In the 1930s, researchers at the University of Florida helped develop new hybrid grape varieties from the indigenous Muscadine to be more ecologically suitable for Florida's climate, including Blanc du Bois, Stover, Swanee, Daytona, Orlando Seedless and Miss Blanc.

[7][8] As early as 1991 Florida Orange Groves Winery began to develop wines made from 100% tropical fruit.

Thanks to their efforts the term Florida Wine now encompasses varieties like mango, key lime, orange, grapefruit, blueberry and strawberry.