Spain re-established diplomatic relations with Lithuania after its independence restoration on September 7, 1991, and accredited – until the opening of the resident Embassy in 2004 – the Spanish Ambassador in Copenhagen.

[citation needed] Lithuania is of growing interest for Spain due to the strengthening of the Nordic and Baltic dimension of the European Union that led to the extension of it in 2004.

In this sense, Spain has participated in 9 Twinning projects of the European Union: The Spanish embassy also organized, in coordination with the Ministry of Foreign Affairs of Lithuania and the Spanish Ministry of Economy and Finance, a seminar on the management of structural and cohesion funds, on November 26, 2004, at the premises of the Embassy, addressed to local, regional and institutional Lithuanian administrations.

The Spanish embassy also coordinated, together with the Lithuanian Ministry of Foreign Affairs and the Ministry of Economy and Finance, the organization of a seminar on structural funds in order to present the Spanish experience in the use of these that was held in March 2007 in Madrid and Toledo, and in which the Lithuanian Central Agency for CPVA projects participated (competent in the execution of the structural funds granted to this country).

Within the framework of this cooperation in the field of security, the NATO mission for the protection of the Baltic airspace, which from August 1 to December 1 on 2006, assumed Spanish Air Force from the base of Siauliai.