The Little Snake River is a tributary of the Yampa River, approximately 155 miles (249 km) long, in southwestern Wyoming and northwestern Colorado in the United States.

It rises near the continental divide, in Routt National Forest in northern Routt County, Colorado, along the northern edge of the Park Range.

[2] It turns southwest and flows through Moffat County, Colorado, joining the Yampa approximately 45 mi (72 km) west of Craig, just east of Dinosaur National Monument.

The Little Snake is not generally navigable except seasonally in years of plentiful water.

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