In anatomy, a lobe is a clear anatomical division or extension[1] of an organ (as seen for example in the brain, lung, liver, or kidney) that can be determined without the use of a microscope at the gross anatomy level.

This is in contrast to the much smaller lobule, which is a clear division only visible under the microscope.

[2] Interlobar ducts connect lobes and interlobular ducts connect lobules.

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