At 3,415 feet (1,041 m), it provides a much lower crossing of the Cascade Range near Mount Hood than the 4,650-foot (1,420 m) Oregon Route 35 Bennett Pass on the southeast side.

The road through the pass was initially established by Native Americans, as a trading route connecting the Willamette Valley and sites at the eastern end of the Columbia River Gorge like Celilo Falls.

The 1846 construction of the Barlow Road provided a less daunting alternate route around the south side of Mount Hood.

By 5 miles (8 km) south of Lolo Pass, the Pacific Crest Trail drops to 2,800 feet (850 m) and much lower to the north at the Columbia River.

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