Musically, "Look at Me Now" is a "dirty south–inspired" hip hop song that features "thumping bass, spacy synth and horn jam sounds."

It features numerous scenes of Brown, Busta Rhymes, and Lil Wayne in a smoke-filled, graffiti-covered parking garage, where a Step Up-type dance-off is held.

Several artists have covered the song and released their own remixes, including Karmin, Justin Bieber, Trey Songz and Da Brat.

[9] Over a hip hop drum beat that evokes Cali Swag District's 2010 single "Teach Me How to Dougie", "Brown sings that he's still riding high (in a yellow Lamborghini, to boot) before venturing off into a typically tasteless discussion of his manhood", according to staff members from Idolator.

"[11] Akshay Bhansali from MTV News wrote that "Look at Me Now" features "a fast-rapping flurry of awesome self-indulgence courtesy of Busta Rhymes, Lil Wayne and Chris, with an eerie downtempo beat cooked up by chefs Afrojack and Diplo.

[16] The video begins with scenes of Brown wearing a mirrored mask inside a giant birdcage, before switching to a dance routine in a smoke-filled, graffiti-covered parking garage.

[17] When Brown raps his verse, he is seen standing next to Rhymes, wearing horn-rimmed glasses, a red Brooklyn cap, and a white baseball jersey, which was the signature look of Mars Blackmon from the 1986 film, She's Gotta Have It.

Brad Wete from Entertainment Weekly wrote that in the video, "Busta's rapid fire flow and Weezy's frenetic verse pretty much blow Chris' off the track.

"[18] Ed Easton Jr. from WXRK wrote that the video was "cool and fun to watch", and added that "the random array of colors displayed by Breezy and company definitely keeps you locked in as a viewer.

Tour, he made a guest appearance at Canadian recording artist Justin Bieber's concert at the Acer Arena in Sydney on April 28, 2011, where they performed "Look at Me Now" together.

Rhymes later appeared from a brightly lit cube flanked by dancers in eerie, transparent masks illuminated by blinking lights.

Wearing a black jacket with enormous, ridged sleeves, Rhymes dropped the microphone after performing his verse and walked off the stage.

Brown ended the performance with "Paper, Scissors, Rock", a song from F.A.M.E..[28] American R&B singer Trey Songz released a remix of "Look at Me Now" via Twitter on February 4, 2011.

[31] Justin Bieber performed "Look at Me Now" during his My World Tour in Tel Aviv, Israel on April 14, 2011, where he covered Brown and Rhymes' verses.

[32] On November 30, 2011, American rapper Mac Lethal released a cover video of the song onto YouTube, in which he performs a version with his own lyrics while simultaneously cooking pancakes.

Jon Caramanica of The New York Times gave "Look at Me Now" a positive review, praising Diplo and Afrojack's "fabulous, insidiously catchy production" and wrote that the song was the highlight on F.A.M.E..[11] Tom Howard of Yahoo!

Music wrote that the song was "the album's standout track... which benefits from some truly excellent bleepy production and a vocal savagery lacking anywhere else.

"[34] Joanne Dorken of MTV UK called it an "uptempo dance-floor filler", also writing that it was one of the standout tracks on the album "with its unforgettable beats.

"[35] Sean Fennessey of The Washington Post called the track a "space-age sonic bender" and wrote that it's "the most prominent of Brown's surprisingly deft, if extraneous, attempts at rap.

[7] Eric Henderson of Slant Magazine could not imagine why Brown would want to share the song with Lil Wayne and Busta Rhymes, stating "One alone would've been enough to point up just how little personality he exudes on his own tracks, but putting both on 'Look at Me Now' ironically renders him invisible.

"[6] Chad Grischow of IGN wrote, "Brown tries his hand at rapping on the out-of-place 'Look at Me Now', and is left in the dust by Lil Wayne and, suddenly resurgent, Busta Rhymes.

"[8] Staff members of Idolator criticized Brown for trying to sound like a second-class Soulja Boy Tell 'Em and praised Busta Rhymes' "razor sharp verse" as the song's highlight.