Loon (monkey)

[3] Treatment began immediately, with multiple daily blood draws and insulin injections; however, this led Loon to become extremely aggressive, and the zoo was forced to restrain him in a small cage, and to sedate him before procedures.

[3][4] With the help of a former SeaWorld animal trainer,[5] zoo personnel used operant conditioning techniques so that Loon would associate venipuncture and other medical procedures with rewards such as getting fed or groomed.

He subsequently learned to participate in getting himself weighed,[3] and to provide daily urine samples by "go[ing] potty" on command.

[4][6] Due to physical consequences of his diabetes, Loon was unable to breed naturally;[6] however, his semen was assigned to the Columbus Zoo, where female drills are available for artificial insemination.

[4] As well, he was one of the first two animals of an endangered species to have his tissue samples used to make induced pluripotent stem cells as an attempt at conservation.