Lost Creek Lake is a reservoir located on the Rogue River in Jackson County, Oregon, United States.

The lake is impounded by William L. Jess Dam which was constructed by the U.S. Army Corps of Engineers in 1977 for flood control and fisheries enhancement.

In 1996, the Congress renamed Lost Creek Dam, along with the adjoining intake structure, in honor of William L. Jess, one of the founders of the Rogue Basin Association, which was established in 1955.

With average rainfall the lake is around 3,430 acres and 280 feet in depth, providing plenty of area for summertime watersports such as boating, skiing, wake boarding, tubing, and jet-skiing.

The Lost Creek Lake is a popular year round spot for trout and small mouth bass fishing.

In addition to boat storage and rentals, the marina features on water fueling, a bait and tackle shop, and a small store and restaurant.